Topics in Oral Medicine

Vesiculobullous Disorders

From the DentTest dentistry textbook, with 121 practice questions. Last updated 8 October 2026.

Differential Diagnosis

Congenital

Acquired

Subcorneal

  • Most of these conditions spare the oral mucosa

  • Staphylococcal scalded skin syndrome

Intraepidermal

  • Epidermolysis bullosa simplex

  • Hailey-Hailey disease

  • Darier disease

  • Acute eczema

  • Hand, foot and mouth disease

  • Herpes simplex

  • Pemphigus vulgaris

  • Paraneoplastic pemphigus

  • Varicella-zoster

Subepidermal

  • Junctional epidermolysis bullosa

  • Dystrophic epidermolysis bullosa

  • Angina bullosa haemorrhagica

  • Bullous lichen planus

  • Dermatitis herpetiformis

  • Epidermolysis bullosa acquisita