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Zinc Oxide-Eugenol Cement

From the DentTest dentistry textbook. Last updated 6 August 2026.

Definition: A cement formed by chelation between zinc oxide and eugenol (from clove oil), producing zinc eugenolate in the presence of moisture, often reinforced with resins or other fillers for improved strength.

Clinical Case

A 38-year-old patient presents with a very deep occlusal carious lesion on a lower first molar. After careful excavation, the remaining dentine is thin and leathery, and the tooth is symptomatic but vital. You plan to place an amalgam restoration, but you want a pulp-soothing lining that provides good thermal insulation and can be placed quickly. You choose a reinforced zinc oxide–eugenol (ZOE) cement as a base, possibly combined with a zinc phosphate base above if needed.

Uses

  • Cavity linings/bases in deep cavities under metallic restorations, particularly amalgam.

  • Temporary luting cement for provisional crowns and bridges.

  • Temporary filling material (intermediate restorations).

  • Components of some endodontic root-canal pastes (covered in the endodontics chapter).

How to use them in clinical practice?

  1. Select formulation

    • Powder/liquid system or paste/paste system.

    • Reinforced ZOE if additional strength is desired.

  2. Prepare the tooth

    • Remove caries as indicated.

    • Rinse and gently dry; a small amount of residual moisture will aid setting but avoid puddles.

  3. Dispense

    • Powder/liquid: scoop powder and add recommended drops of liquid.

    • Paste/paste: extrude equal lengths of base and catalyst pastes onto a mixing pad.

  4. Mix

    • Blend quickly to a homogenous, creamy or putty-like consistency, depending on intended use.

    • For bases: aim for a thicker, more body-rich mix.

    • For temporary luting: aim for a smoother, more flowable mix.

  5. Place

    • For linings/bases: place a uniform layer over the pulpal floor or deepest area; avoid covering all walls if an adhesive restorative will be used later.

    • For temporary luting: apply to the fitting surface of the provisional restoration and seat.

  6. Set and follow-up

    • Allow the material to set under the influence of oral moisture and temperature.

    • For bases, proceed with overlying base (if planned) and definitive restoration once sufficiently set.

Constituents

  • Powder

    • Zinc oxide (primary reactive component)

    • Zinc acetate (1–5%) as an accelerator

    • Optional resin (e.g. hydrogenated rosin, polystyrene) in reinforced ZOE to improve strength

  • Liquid

    • Eugenol (active chelating agent)

    • Vegetable oil (e.g. olive oil, 5–15%) to control viscosity

Chemistry

The key reaction is chelation:

  • Zinc oxide + water → zinc hydroxide + eugenol → zinc eugenolate

    • Zinc eugenolate can readily undergo hydrolysis forming zinc hydroxide and eugenol again.

  • The reaction is very slow in the absence of water, but in the moist environment of a cavity:

    • Residual dentinal moisture and saliva accelerate setting dramatically.

    • Oral temperature further speeds the process

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